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The Weinstein Laboratory

The Laboratory of Molecular Genetics (LMG)

The Laboratory of Molecular Genetics (LMG), headed by Dr. Igor Dawid, is one of a number of Laboratories (more or less equivalent to university academic departments) in the National Institute of Child Health and Human Development (NICHD). The nine LMG faculty members work with a diverse range of model organisms, including bacteria, viruses, Drosophila, Xe\nopus, and zebrafish. Three LMG groups are using the zebrafish; the Weinstein lab, Chitnis lab, and Dawid lab. LMG facilities include:

Zebrafish Housing Facilities - three separate fish facilities (2 "clean" facilities of approximately 3000 tanks each and a 168 tank quarantine facility), with all fish feeding and facility maintenance provided by a full-time animal care staff.

Microscopic Imaging Facilities - two microscopy rooms supplied with the latest equipment, including 3 confocal microscopes (a Bio-Rad Radiance multiphoton, Zeiss LSM, and Olympus), automated digital time lapse microscopy stations built on Axiophot II microscopes, laser cell ablation/fluorescent dye uncaging & electrophysiology rigs, numerous fluorescence-equipped dissecting microscopes, etc. Many additional advanced microscopic tools are available nearby on the NIH campus, including laser capture microdissection facilities.

Molecular Biology Facilities - a generous assortment of up to date molecular biology equipment, including hgh-throughput ABI and Beckman capillary sequencers, high-throughput PCR & mapping capability (MJ tetrads, etc), several automated in situ hybridization/immunohistochemistry machines, lightcycler, etc.